NucleoRich PL

Conveniently located to serve the areas of Lake Oswego, Portland, OR and Woodburn, OR

NucleoRich PL

NucleoRich PL is a revolutionary approach to achieving a youthful appearance and rejuvenated skin. This comprehensive  3-stage treatment combines the power of hyaluronic acid, polynucleotides, and polylactic acid to address multiple signs of aging. This includes wrinkle reduction, fine line smoothing, age spot removal, collagen stimulation, skin firming, and elasticity restoration.

At the Aesthetic Laser Center, Dr. Quita Lopez, a highly skilled and experienced cosmetic surgeon, offers the NucleoRich PL anti-aging treatment to her patients in Lake Oswego. With a deep understanding of the intricacies of facial anatomy and a commitment to delivering natural-looking results, Dr. Lopez can help you achieve your aesthetic goals.

If you’re looking to turn back the clock and achieve a more youthful, vibrant complexion, consider scheduling an appointment with Dr. Lopez. To get started, give us a call at (503) 607-8201 or contact us online to learn more about the NucleoRich PL. Rediscover your natural beauty and regain your confidence with this innovative approach to skin rejuvenation.

The Fight Against Skin Aging

As we age, our skin undergoes significant changes. Collagen and elastin levels decline, leading to the formation of wrinkles and fine lines. Additionally, factors such as sun exposure, lifestyle choices, and genetics can further contribute to the aging process, (1) leaving us longing for a solution that can turn back the hands of time.

NucleoRich PL offers a remarkable approach to combat these signs of aging. This treatment utilizes the power of polynucleotides, which are essential building blocks found in our DNA. When introduced into the skin, polynucleotides stimulate cellular activity, promoting the production of collagen and elastin. As a result, the skin becomes firmer, smoother, and more youthful-looking.

But NucleoRich PL doesn’t stop there. It also contains polylactic acid, a biocompatible substance known for its ability to stimulate natural collagen production. By combining these two potent ingredients, this treatment provides a comprehensive solution for skin rejuvenation, tackling multiple aspects of the aging process simultaneously.

One of the notable benefits of NucleoRich PL is its versatility. It can be used as a standalone treatment or combined with other cosmetic procedures, such as dermal fillers to enhance its effects. Our skilled plastic surgeon, Dr. Quita Lopez, will carefully evaluate your unique needs and design a customized treatment plan tailored specifically to you.

NucleoRich PL Active Ingredients

Hyaluronic Acid

Hyaluronic acid (HA) is a remarkable substance that plays a vital role in our bodies, particularly when it comes to maintaining the health and appearance of our skin. It is a naturally occurring carbohydrate molecule found in our connective tissues, joints, and eyes, and it serves multiple functions.

HA stimulates collagen production, which is essential for maintaining the elasticity and firmness of our skin. Collagen is a protein that gives our skin its structural support, and as we age, its production naturally declines. By promoting collagen synthesis, hyaluronic acid helps to restore volume and elasticity to the skin, resulting in a more youthful and vibrant appearance.


Polynucleotides are essential components of genetic material. They consist of DNA and RNA, which play crucial roles in the functioning of our cells. DNA, or deoxyribonucleic acid, is a double-stranded molecule that forms the famous double helix structure. It carries the genetic instructions for all living organisms, determining our unique characteristics and traits.

In recent years, advancements in technology have allowed us to harness the power of polynucleotides for aesthetic purposes as well. Polynucleotide-based treatments, often referred to as PN or PDRN therapy, offer a unique approach to skin rejuvenation and hair restoration. By utilizing the regenerative properties of polynucleotides, these treatments promote collagen synthesis, enhance tissue repair, and stimulate cellular growth.


Glutathione is a naturally occurring substance in our bodies that plays a crucial role in detoxification, neutralizing harmful free radicals, and supporting liver function. It acts as a shield, protecting our cells from oxidative stress (3) and damage caused by environmental factors, aging, and lifestyle choices.

Polylactic Acid

Polylactic acid, or PLA, is a remarkable biodegradable polymer that has captured the attention of various industries for its exceptional properties. It is an extraordinarily versatile substance that is not only used in medical sutures but also in cosmetic procedures as it stimulates collagen production in the skin. This makes it an excellent option for those who want to improve the appearance of fine lines, wrinkles, and volume loss.

The NucleoRich System

Using the latest science, NucleoRich PL can produce “molecular lifting” on a microscopic scale. Each system contains 3 vials:

  • Nucleorich Yal 1x5ml, HA
  • Nucleorich Polynucleotides 1x3ml, polynucleotides, HA, and glutathione
  • Nucleorich Powder 1x50mg micronized PLA powder

How is NucleoRich Different?

NucleoRich PL anti-aging treatment not only addresses existing signs of aging but also helps prevent further deterioration of the skin. By restoring the skin’s elasticity and promoting collagen synthesis, this treatment provides long-lasting results that enhance your overall appearance. One recent study concluded that polynucleotides are a valuable and effective option in anti-aging, rapidly smoothing skin texture, and improving skin quality. (2)

Benefits of NucleoRich PL

  • Younger-looking skin: The NucleoRich PL treatment effectively targets multiple signs of aging, helping you achieve a more youthful and rejuvenated appearance.
  • Reduced appearance of wrinkles and fine lines: Through its unique formulation, NucleoRich PL diminishes the visibility of wrinkles and fine lines, promoting smoother and more refined skin texture.
  • Improved skin elasticity: As we age, our skin loses its natural elasticity, resulting in sagging and drooping. This treatment revitalizes the skin’s elasticity, restoring a firmer and more lifted appearance.
  • Even skin tone: Irregularities in skin tone, such as age spots and discoloration, can be visibly reduced with NucleoRich PL. This treatment helps promote a more even and radiant complexion.
  • Stimulated collagen production: Collagen is essential for maintaining the skin’s structure and firmness. NucleoRich PL stimulates the production of collagen, promoting a youthful and resilient complexion.
  • Increased natural radiance and glow: Dull and lackluster skin can be transformed with the NucleoRich PL treatment. Experience a renewed radiance and healthy glow that will leave you looking refreshed and revitalized.
  • Firmed and tightened skin: Loose and sagging skin is a common concern as we age. NucleoRich PL tightens and firms the skin, restoring a more youthful and contoured facial appearance.
  • Diminished age spots and hyperpigmentation: Sun damage and aging can lead to the development of age spots and hyperpigmentation. This treatment targets and minimizes these imperfections, revealing a more even complexion.
  • Minimized signs of sun damage: Prolonged sun exposure can result in visible signs of damage such as sunspots, fine lines, and a rough texture. NucleoRich PL helps to repair and rejuvenate sun-damaged skin, leaving it smoother and more radiant.

Candidates for NucleoRich PL

Candidates for NucleoRich PL treatment at Aesthetic Laser Center are individuals seeking advanced skincare solutions for skin rejuvenation, wrinkle reduction, collagen production, skin firming, and the improvement of fine lines and age spots.

Ideal candidates for this treatment are those who want to address signs of aging without undergoing invasive procedures such as a facelift or mini facelift. They may have concerns about sagging skin, wrinkles, loss of elasticity, or uneven skin tone. It is important that candidates are in good overall health and have realistic expectations for the outcome of the treatment.

Personal Consultation

If you’re tired of aging skin, your first step toward facial rejuvenation is a consultation at our Lake Oswego office. During your personal consultation with Dr. Lopez, she will carefully assess your unique needs and develop a customized treatment plan tailored to your specific concerns. 

How Much is NucleoRich PL in Lake Oswego?

The cost of the NucleoRich PL anti-aging treatment at Aesthetic Laser Center will depend on various factors specific to each patient’s individual treatment plan. During your personal consultation with Dr. Quita Lopez, she will assess your needs and determine the most appropriate techniques to address your concerns. To schedule your one-on-one consultation with Dr. Lopez, please call our office at (503) 607-8201

For more information about our non-surgical procedures, please see our blog.


Is NucleoRich PL suitable for all skin types?

Yes, NucleoRich PL is suitable for all skin types. It is carefully formulated to be gentle yet effective, making it suitable for even sensitive skin. Whether you have dry, oily, or combination skin, NucleoRich PL can help address various signs of aging and improve your skin’s overall health and appearance.

How long does it take to see results with NucleoRich PL?

The results of NucleoRich PL treatment may vary depending on individual factors such as age, skin condition, and treatment frequency. However, many patients start noticing improvements in their skin texture and tone within a few weeks of starting the treatment. With consistent use and adherence to the recommended skincare routine, the results become more pronounced over time, leading to a more youthful and radiant complexion.

Are there any side effects or downtime associated with NucleoRich PL treatment?

NucleoRich PL treatment is minimally invasive and generally well-tolerated by most patients. Some individuals may experience mild redness or temporary sensitivity immediately after the treatment, but these side effects typically subside within a few hours. There is no significant downtime associated with NucleoRich PL, allowing patients to resume their daily activities immediately after the procedure. It is important to follow the post-treatment instructions provided by your healthcare provider to ensure optimal results and minimize any potential risks.


  1. Chaudhary M, Khan A, Gupta M. Skin Ageing: Pathophysiology and Current Market Treatment Approaches. Current Alzheimer Research. 2019;16. doi: 
  2. Araco A, Araco F, Raichi M. Clinical efficacy and safety of polynucleotides highly purified technology ( PN‐HPT ®) and cross‐linked hyaluronic acid for moderate to severe nasolabial folds: A prospective, randomized, exploratory study. Journal of Cosmetic Dermatology. 2022;22(1):146-155. doi: 
  3. Kwon D, Cha HJ, Lee H, et al. Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway. Antioxidants. 2019;8(4):82. doi: